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Compared to the untreated control, the senescence level in FOXO4-DRI treated PDL9 chondrocytes was significantly reduced

This includes the peptide and CTR (including the ECD position) that adopt the same conformation to those observed in Cagri-bound AMYR-Gs complexes, assessed by overlaying the backbones of the structures (Fig

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Indeed, ALT telomeres have a relaxed telomeric chromatin configuration (compared to telomerase positive and normal cells) making them more susceptible to DNA damage and telomere elongation through ALT (Lin et al 2021

Peptides play crucial roles in various physiological processes, from cell signaling to immune function